Spike2 has built-in detection of waveform features, measurements of latencies, amplitudes and areas as well as averages and trend plots. Further custom analysis functions can be applied via a script language.

  • Generate tachogram channels based on detected waveform complex segments, such as ECG R-waves for heart rate variability studies
  • Locate repolarisation percentages and measure latencies from cardiac action potentials
  • Measure systolic and diastolic blood pressures on a beat-by-beat basis. Use detected peaks and troughs to calculate and plot mean blood pressure
  • Mark and measure responses to drug applications

Waveform processing
Click to play video

This video tutorial shows how to generate heart rate
blood pressure trace using active cursors

Spike2 can apply channel processes (for example, rectification and smoothing) on-line and off-line to aid with the detection and measurement of waveform features. Virtual channels allow inter-channel arithmetic, such as calculating the third lead in Einthoven's triangle.

  • Locate and mark points of interest in processed data. Use these reference markers to take measurements from the original signal
  • Data processing options include digital filtering and smoothing to reduce noise and unwanted frequencies, differentiation to enable detection of hard to find components, and DC remove to normalise the signal and minimise baseline drift
  • Applied processes only affect the displayed data, not the original stored on disk
  • Create duplicate channels to show raw and processed data simultaneously

Cardiac action potential analysis


Results from cursor positions, correlations, averages and script driven functions can be plotted and exported for further analysis, if required.

  • Available measurements include: mean waveform value, slope, curve area, ratios, differences, and peak-to-peak amplitude
  • Take multiple measurements based on cursor positions
  • Plot results to new channels in the data file or XY scatter plots
  • Export results to spreadsheet

Trend plot of multiple measurements


Spike2 can perform on-line and off-line detection of waveform features and mark these in a new channel in the data file using the built-in active cursor and measurement functions. This video tutorial shows how to generate heart rate from a blood pressure trace.

  • Alpha MED Sciences
  • Alpha Omega Engineering
  • Axon Instruments
  • Binary data
  • Bionic/Cyberkinetics
  • Biopac
  • CED SON (Macintosh)
  • CONSAM (D. Colquhuon)
  • DATAQ Instruments (Codas)
  • DataWave
  • Data Sciences International
  • Delsys Files
  • European Data Format(+)
  • Grass-Telefactor (PolyView)
  • HLR Data Format
  • Heka Data Format
  • Multi Channel System (Mc_Rack)
  • MindSet (16/24) data Files
  • MindWare data files
  • Motion Labs Systems Files .c3d
  • NeuroScan
  • Neuralynx
  • Plexon
  • RC Electronics
  • Text files
  • TMS International
  • Tucker-Davis Technologies
  • WAV (Microsoft)
  • WaveMetrics Igor Pro (PC/Mac)
  • Xltek Neuroworks
Cambridge Electronic Design Limited

Registered in England: 972132

Registered office:

  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ

VAT: GB 214 2617 96

Producer Registration number: WEE/BD0050TZ

Terms and Conditions of Sale

For our US customers, we can provide tax form W-8BEN, that identifies us as a UK company.

DUNS: 219151016
NAICS: 423490
Commodity codes
Hardware: 84716070
Software: 85234945

By email:

By post:
  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
By telephone:

(Int.+44) (0)1223 420186

From North America (Toll Free):

1 800 345 7794


Privacy policy

CED, through this site, does two things that relate to privacy. We would like to explain them.

Emails from down-loads

We offer free down-loads of many files on our site, from test programs to complete install files for updated versions of major packages like Spike2 and Signal.

When customers wish to take a down-load of a major package, we ask a few questions, including their name, email address, the serial number of the software for which they seek an upgrade and whether they would like an automatic email whenever we update the product. This information is emailed back to CED when they access the final down-load screen. Within this email, your browser transmits the type and version of browser you are using, and the screen resolution you are running.

The reasons why we take and keep this information are that it is useful for our software development team to know who has taken the latest versions, and it is useful for our web site development team to know which browsers people are using to view our site, and what resolution they have their screens set to.


When people down-load a major package, we try to write a cookie, a small file in your computer, that records your name, serial number of the software package, and the version you are down-loading. These files have a lifetime of one year.

The reasons for storing this information are firstly that if you ask for another down-load some other time, your details are read from the cookie and are pre-written into the form, to save you looking them up again. The other reason is that next time you access our site, your browser looks through your CED cookies and compares the versions down-loaded with the latest version numbers read from our site. If there is a later version of a product you have already down-loaded, we tell you on the home page screen, so you know that it is worth going to the down-load page again.

None of this information is ever given to anyone outside CED. ×