Patch clamp

Signal for Windows incorporates many powerful features for whole cell and single channel experiments that make it ideal for electrophysiological recording. Familiar terms, and easily set up protocols for standard requirements enable the user to get started quickly using Signal and a CED 1401 data acquisition interface. Signal also incorporates an import function allowing you to analyse data from other recording systems.

Clamp specific sampling support
  • Nominate a particular recording state to be used for seal and membrane resistance measurements.
  • Easy adjustment of holding potentials.
  • Dynamic readout of seal resistance.
  • Support for dynamic clamp studies with up to 15 selectable conductance models. Update rates of over 300kHz without timing jitter - see details.

Single channel patch clamp analysis

  • Membrane analysis option displays measurements of total resistance, access and membrane conductance, capacitive transient decay time constant and membrane capacitance.
  • Display selected measurements as a graph against time.
Amplifier communication
  • Telegraph communication to set channel scales based on voltages supplied from a wide range of patch clamp amplifiers.
  • Direct software communication with Molecular Devices MultiClamp 700 and Axoclamp 900 amplifiers. Reads values for gains, filter settings, membrane capacitance, series resistance and external command sensitivity. The values read are stored in the Signal data file.

Membrane analysis during sampling

Cambridge Electronic Design Limited

Registered in England: 972132

Registered office:

  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
  • ENGLAND.

VAT: GB 214 2617 96

Producer Registration number: WEE/BD0050TZ

Terms and Conditions of Sale

For our US customers, we can provide tax form W-8BEN, that identifies us as a UK company.

DUNS: 219151016
CAGE/NCAGE: KB797
NAICS: 423490
Commodity codes
Hardware: 84716070
Software: 85234945
×

By email:

info@ced.co.uk

By post
  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
  • ENGLAND.
By telephone:

(Int.+44) (0)1223 420186

From North America (Toll Free):

1 800 345 7794

×

Privacy policy

CED, through this site, does two things that relate to privacy. We would like to explain them.

Emails from down-loads

We offer free down-loads of many files on our site, from test programs to complete install files for updated versions of major packages like Spike2 and Signal.

When customers wish to take a down-load of a major package, we ask a few questions, including their name, email address, the serial number of the software for which they seek an upgrade and whether they would like an automatic email whenever we update the product. This information is emailed back to CED when they access the final down-load screen. Within this email, your browser transmits the type and version of browser you are using, and the screen resolution you are running.

The reasons why we take and keep this information are that it is useful for our software development team to know who has taken the latest versions, and it is useful for our web site development team to know which browsers people are using to view our site, and what resolution they have their screens set to.

Cookies

When people down-load a major package, we try to write a cookie, a small file in your computer, that records your name, serial number of the software package, and the version you are down-loading. These files have a lifetime of one year.

The reasons for storing this information are firstly that if you ask for another down-load some other time, your details are read from the cookie and are pre-written into the form, to save you looking them up again. The other reason is that next time you access our site, your browser looks through your CED cookies and compares the versions down-loaded with the latest version numbers read from our site. If there is a later version of a product you have already down-loaded, we tell you on the home page screen, so you know that it is worth going to the down-load page again.

None of this information is ever given to anyone outside CED. ×