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Analysis

Leak subtraction
  • 3 methods of defining leak data on-line and off-line
  • On-line and off-line subtraction of scaled leak trace, including capacitive transients
  • Subtract specific leaks on-line in current clamp using a selection of dynamic clamp models

Measurement plots

The trend and measurement plot function in Signal generate graphs of measurements taken from the recorded data both on-line and off-line. For each frame selected, measurements are taken from individual or multiple events and plotted as X and Y coordinates. Typical examples would be the generation of an IV curve or measurements from multiple action potentials.

Analysis of paired recording from a pyramidal cell
connected with a fast spiking interneurone in the cortex†


Curve fits

Fit mathematical functions to original or leak subtracted data and trend plots.

  • Fit types include:

    • Exponential, first or second order
    • Gaussian, one or two
    • Polynomials from first to fifth order
    • Sigmoid (Boltzmann) curve
  • Gives best fit coefficients and an estimate of confidence
  • Display fit coefficients in trend plots

 

Exponential curve fitting on multiple traces

† Data courtesy of Dr. Afia Ali, London School of Pharmacy

Cambridge Electronic Design Limited

Registered in England: 00972132

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  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
  • ENGLAND.

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For our US customers, we can provide tax form W-8BEN, that identifies us as a UK company.

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info@ced.co.uk

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  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
  • ENGLAND.
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