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Data acquisition using a CED 1401

  • Record to the 64-bit format of virtually unlimited size and duration or use the established 32-bit format for backwards compatibility
  • Set different waveform sample rates per channel
  • Capture and classify single and multi-unit spike activity in real-time
  • Continuous, internally timed and triggered recording modes
  • Store up to 8 channels of event data with microsecond timing resolution
  • Log accurately timed coded 8-bit digital inputs
  • Annotate data records with text notes and keyboard markers
  • Sample data from other equipment using the CED Talker interface

Spike2 sampling configuration dialog

  • Swap between experiment setups quickly with a single mouse click
  • Calibrate waveforms with multiple methods including values, areas, slopes
  • Automatically save and sequence multiple files with optional trigger start
  • Recover data files in the event of an un-commanded system shutdown
  • Configure dynamically programmable amplifiers including the CED1902, the Digitimer D360 (32-bit only), D440 and the Power1401 gain option

System requirements

Spike2 version 10 requires a CED intelligent laboratory interface (Power1401, a Micro1401Mk II or later) and a PC (or Intel Macintosh) with Windows 7, 8, 10 or 11. See the compatibility table. The computer must be modern enough to support the SSE2 instruction set. We recommend that the PC has a minimum of 8GB RAM and runs Windows 10.

Heart rate and blood pressure variability analysis
including Poincare plot with fitted ellipse

Both 32-bit and 64-bit versions of Spike2 are supplied: either version of the software can be used on systems running a 64-bit OS. The 64-bit version provides a performance increase and access to more memory.

Test computer for SSE2 compatibility

The latest versions of Spike2 and Signal require the SSE2 instruction set extension to the IA32 (x86) instruction set. It started to be added to Intel 32-bit CPUs in 2000 and to AMD CPUs in 2003. All 64-bit capable CPUs support this. The following link has a little more information:


If you are unsure about your computer, to test it for compatibility, please download SSE2check.zip, extract SSE2check.exe and run it to get a direct answer. ×

Cambridge Electronic Design Limited

Registered in England: 00972132

Registered office:

  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ

VAT: GB 214 2617 96

Producer registration number: WEE/BD0050TZ

Terms and Conditions of Sale

For our US customers, we can provide tax form W-8BEN, that identifies us as a UK company.

DUNS: 219151016
NAICS: 423490
Commodity codes
Hardware: 84716070
Software: 85235190

By email:


By post:
  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
By telephone:

(Int.+44) (0)1223 420186

From North America (Toll Free):

1 800 345 7794