Stimulus generation

Signal can generate stimulus outputs on up to 8 analogue and 16 digital lines from a CED 1401 interface. A graphical pulse editor provides a user-friendly display for fast and easy creation of stimulus protocols. For more complex output and control requirements there is also a text editor which gives direct access to the sequencer instruction code.

  • Drag-and-drop pulses and analogue waveforms from a palette onto output tracks in the editor
  • Modify pulse parameters including timings and amplitudes quickly and easily, even during sampling
  • Create up to 256 sets of up to 500 pulses
  • Outputs can be fixed or change amplitude and duration on repeats
  • Define pulse protocols for automated stimulus sequencing using multiple states and automatically record the stimulus used with each response
  • Switch between stimulus protocols at the click of a button

Pulses configuration dialog

Control of current and voltage stimulators

Precisely timed TTL pulses delivered from the 1401 interface can trigger a wide range of constant current and constant voltage electrical stimulators. Constant current devices such as the DS4, DS5 and DS8R stimulators available from Digitimer will output a constant current stimulus proportional to an input analogue voltage waveform generated by the 1401.

Magnetic stimulator control

Signal's built-in auxiliary states system provides direct control of magnetic stimulators during sampling, including adjusting stimulus amplitude and timing and checks on stimulator condition. All settings are stored with the corresponding data frame.
See a video demonstration or our TMS application guide.

Motor evoked potential analysis with trend plot of
amplitude versus stimulus intensity


Multiple states control of supported Magstim devices is achieved using the auxiliary states module in Signal. The Magstim button in the States tab then allows the user to configure settings for Magstim 2002, BiStim2 or Rapid devices. This video tutorial demonstrates how to set up Magstim configurations in Signal.

Cambridge Electronic Design Limited

Registered in England: 972132

Registered office:

  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ

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Terms and Conditions of Sale

For our US customers, we can provide tax form W-8BEN, that identifies us as a UK company.

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NAICS: 423490
Commodity codes
Hardware: 84716070
Software: 85234945

By email:

By post:
  • Cambridge Electronic Design Limited,
  • Technical Centre,
  • 139 Cambridge Road,
  • Milton,
  • Cambridge CB24 6AZ
By telephone:

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Privacy policy

CED, through this site, does two things that relate to privacy. We would like to explain them.

Emails from down-loads

We offer free down-loads of many files on our site, from test programs to complete install files for updated versions of major packages like Spike2 and Signal.

When customers wish to take a down-load of a major package, we ask a few questions, including their name, email address, the serial number of the software for which they seek an upgrade and whether they would like an automatic email whenever we update the product. This information is emailed back to CED when they access the final down-load screen. Within this email, your browser transmits the type and version of browser you are using, and the screen resolution you are running.

The reasons why we take and keep this information are that it is useful for our software development team to know who has taken the latest versions, and it is useful for our web site development team to know which browsers people are using to view our site, and what resolution they have their screens set to.


When people down-load a major package, we try to write a cookie, a small file in your computer, that records your name, serial number of the software package, and the version you are down-loading. These files have a lifetime of one year.

The reasons for storing this information are firstly that if you ask for another down-load some other time, your details are read from the cookie and are pre-written into the form, to save you looking them up again. The other reason is that next time you access our site, your browser looks through your CED cookies and compares the versions down-loaded with the latest version numbers read from our site. If there is a later version of a product you have already down-loaded, we tell you on the home page screen, so you know that it is worth going to the down-load page again.

None of this information is ever given to anyone outside CED. ×