Spike2 together with a 1401 interface can sample waveform and timing pulse data from a wide variety of equipment. However, some types of measurement devices do not have such convenient outputs. Often the data they generate needs some computer processing to convert it into a useful format.

A Talker device interface is a program that allows us to take data streams from arbitrary devices in real time and add them into the Spike2 data file as if they were being sampled by the 1401. You can view the data from the device in the same way that you can view data sampled by the 1401 interface, with the same convenient viewing modes and data processing tools. See details →

TIB - Talker Interface Box

The 4703 Talker Interface Box TIB acts as an interface between Spike2 and sensors that use an SPI or I2C interface, such as the InvenSense MPU9250. A TIB connects to the computer via a USB interface and is controlled by the TIBTalk program, which provides the Talker interface to Spike2.

Talker interface box

UK Training days - 16 & 17 March 2017

Our annual UK Training Days have helped many researchers become faster and more efficient at recording and analysing data. Join us in Cambridge and learn how to make the best use of Spike2 and Signal to save time and increase productivity. These sessions are suitable for both existing and prospective users. Training day info →

UK Training Days

New Spike2 version 8

Version 8 is the first release of Spike2 as a 64-bit application. This improves speed and allows access to more memory on the host PC. The data file format has also been rewritten as a 64-bit structure allowing for much larger files and virtually unlimited sampling duration. This has been a large amount of work but gives the program a much more flexible base for further features to be added. Off–line the extended file format enables the import and concatenation of much larger third party files. See history →

Many changes have been made to the script language and sequencer to support 64-bit values. Other changes include increasing the maximum size of user defined dialogs as well as importing of waveform features such as peak and troughs together in a single pass. Improvements to sonogram display calculations, which cope better with gaps in waveform data, and the addition of an intensity key have also been included. See details →


New Signal version 6

Speed improvements have been introduced with the new 64-bit version of the program over the older 32-bit application. A new memory channel type, RealMark, has been added which allows the addition of a time plus up to thirty two individual floating-point values. This type of channel could hold the time of peaks and their corresponding waveform amplitude. The script language has been extended to support locating, adding, deleting and modifying RealMark data. The virtual channel functions have also been improved to accommodate this new channel type. See history →

More development has taken place in the patch and voltage clamp areas with an improved membrane analysis dialog, a duplicate option in the dynamic clamp models dialog and the addition of an optional rectification mode in the noise model. Both standard voltage based telegraphy and the auxiliary telegraphing system can also now operate simultaneously. See details →


New CED 4401 Frequency multiplier

The CED 4401 is designed for use in locking the sampling clock of a CED 1401 data acquisition unit to an external reference frequency, such as those encountered in other sampling systems. Suitable inputs are TTL signals that are stable sub-multiples of 20MHz. The CED 4401 takes this frequency and multiplies it up to the 20MHz needed to feed the external synchronising input of a CED 1401. The power LED on the CED 4401 turns from red to green when a usable input frequency is detected. See details →

4401 Frequency multiplier

New CED 4302 5V signal offsetter

The CED 4302 is a single channel signal offsetter. It adds or subtracts an accurate 5V offset to an analogue input. It is designed for recording unipolar (0V to 10V or -10v to 0V) signals using a ±5V recording system, or for driving equipment that has a unipolar input from bipolar (±5V) output devices.
See details →

4302 5V signal offsetter

New CED 4301 Low Pass Filter

The CED 4301 is a single channel 10th order low-pass filter with manual control of cut-off frequency from 600Hz to 40kHz in 3 switched ranges. The filter passband response is a root-raised-cosine, which gives an almost linear phase characteristic. See details →

4301 Low Pass Filter

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Privacy policy

CED, through this site, does two things that relate to privacy. We would like to explain them.

Emails from down-loads

We offer free down-loads of many files on our site, from test programs to complete install files for updated versions of major packages like Spike2 and Signal.

When customers wish to take a down-load of a major package, we ask a few questions, including their name, email address, the serial number of the software for which they seek an upgrade and whether they would like an automatic email whenever we update the product. This information is emailed back to CED when they access the final down-load screen. Within this email, your browser transmits the type and version of browser you are using, and the screen resolution you are running.

The reasons why we take and keep this information are that it is useful for our software development team to know who has taken the latest versions, and it is useful for our web site development team to know which browsers people are using to view our site, and what resolution they have their screens set to.


When people down-load a major package, we try to write a cookie, a small file in your computer, that records your name, serial number of the software package, and the version you are down-loading. These files have a lifetime of one year.

The reasons for storing this information are firstly that if you ask for another down-load some other time, your details are read from the cookie and are pre-written into the form, to save you looking them up again. The other reason is that next time you access our site, your browser looks through your CED cookies and compares the versions down-loaded with the latest version numbers read from our site. If there is a later version of a product you have already down-loaded, we tell you on the home page screen, so you know that it is worth going to the down-load page again.

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